ATP


SMILES O[C@@H]1[C@@H](COP(=O)(OP(=O)(OP(=O)(O)O)O)O)O[C@H]([C@@H]1O)n1cnc2c1ncnc2N
InChIKey ZKHQWZAMYRWXGA-KQYNXXCUSA-N

Chemical properties

Hydrogen bond acceptors 14
Hydrogen bond donors 7
Rotatable bonds 8
Molecular weight (Da) 507.0

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Endogenous
Approved drug Yes

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
P2Y1 P2RY1 Human P2Y A pKi 4.8 4.8 4.8 Guide to Pharmacology
P2Y4 P2RY4 Human P2Y A pKd 6.2 6.2 6.2 Guide to Pharmacology
P2Y4 P2RY4 Human P2Y A pKi 8.21 8.21 8.21 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
P2Y1 P2RY1 Human P2Y A pIC50 6.1 6.95 7.8 Guide to Pharmacology
P2Y2 P2RY2 Human P2Y A pEC50 6.64 6.87 7.1 Guide to Pharmacology
P2Y4 P2RY4 Human P2Y A pEC50 5.37 5.37 5.37 Guide to Pharmacology
P2Y11 P2Y11 Human P2Y A pEC50 4.2 4.9 5.6 Guide to Pharmacology
P2Y13 P2Y13 Human P2Y A pIC50 5.4 5.4 5.4 Guide to Pharmacology
GPR17 GPR17 Human A orphans A pEC50 7.43 7.43 7.43 Guide to Pharmacology
P2Y4 P2RY4 Rat P2Y A pEC50 5.7 6.0 6.3 Guide to Pharmacology
P2Y1 P2RY1 Rat P2Y A pEC50 6.23 7.21 8.7 ChEMBL
P2Y11 P2Y11 Human P2Y A pEC50 4.76 5.07 5.48 ChEMBL
P2Y1 P2RY1 Wild turkey P2Y A pEC50 5.2 5.43 5.55 ChEMBL
P2Y4 P2RY4 Human P2Y A pEC50 4.37 4.79 5.21 ChEMBL
P2Y2 P2RY2 Human P2Y A pEC50 4.93 6.72 7.52 ChEMBL
P2Y1 P2RY1 Human P2Y A pEC50 5.82 6.26 6.82 ChEMBL
P2Y1 P2RY1 Human P2Y A pEC50 8.22 8.22 8.22 Drug Central
P2Y2 P2RY2 Human P2Y A pEC50 8.15 8.15 8.15 Drug Central
P2Y11 P2Y11 Human P2Y A pEC50 8.29 8.29 8.29 Drug Central
P2Y13 P2Y13 Human P2Y A pIC50 8.27 8.27 8.27 Drug Central
GPR17 GPR17 Human A orphans A pEC50 8.13 8.13 8.13 Drug Central
P2Y1 P2RY1 Wild turkey P2Y A pEC50 8.26 8.26 8.26 Drug Central
P2Y4 P2RY4 Rat P2Y A pEC50 8.2 8.2 8.2 Drug Central
P2Y12 P2Y12 Rat P2Y A pEC50 5.5 5.5 5.5 ChEMBL
P2Y4 P2RY4 Rat P2Y A pEC50 5.75 5.84 5.93 ChEMBL