CHEMBL152756


SMILES COc1cccc(C(=O)NCCCCN2CCN(c3cccc4ccccc34)CC2)c1
InChIKey CQGCCVPXYLTEHT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 417.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 8.64 8.64 8.64 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 9.37 9.37 9.37 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.03 6.03 6.03 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database