LY-255283


SMILES CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1
InChIKey WCGXJPFHTHQNJL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 10
Molecular weight (Da) 360.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
BLT1 LT4R1 Human Leukotriene A pKi 6.89 7.08 7.18 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
BLT2 LT4R2 Human Leukotriene A pIC50 6.82 6.82 6.82 ChEMBL
BLT1 LT4R1 Human Leukotriene A pIC50 7.06 7.07 7.07 ChEMBL
TSH TSHR Human Glycoprotein hormone A Potency 4.7 4.7 4.7 ChEMBL