SB 218795


SMILES COC(=O)[C@@H](c1ccccc1)NC(=O)c1cc(nc2c1cccc2)c1ccccc1
InChIKey IUMQXQJZIHWLIN-HSZRJFAPSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 396.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Human Histamine A pKi 5.86 5.86 5.86 ChEMBL
H1 HRH1 Human Histamine A pKi 5.86 5.86 5.86 PDSP Ki database
SST2 SSR2 Human Somatostatin A pKi 5.0 5.0 5.0 PDSP Ki database
SST3 SSR3 Human Somatostatin A pKi 5.0 5.0 5.0 PDSP Ki database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 5.0 5.0 5.0 PDSP Ki database
SST4 SSR4 Human Somatostatin A pKi 5.0 5.0 5.0 PDSP Ki database
SST5 SSR5 Human Somatostatin A pKi 6.6 6.6 6.6 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database