CHEMBL1078745


SMILES CCOc1cc(CN2CCC(Nc3nc4ccccc4o3)CC2)cc(OC2CCOCC2)c1
InChIKey FDVIZOQPGHRQNB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 451.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.03 7.03 7.03 PDSP Ki database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.03 7.03 7.03 ChEMBL
H1 HRH1 Human Histamine A pKi 5.44 5.44 5.44 PDSP Ki database
H1 HRH1 Human Histamine A pKi 5.44 5.44 5.44 ChEMBL
SST2 SSR2 Human Somatostatin A pKi 5.0 5.0 5.0 PDSP Ki database
SST3 SSR3 Human Somatostatin A pKi 5.0 5.0 5.0 PDSP Ki database
SST4 SSR4 Human Somatostatin A pKi 5.0 5.0 5.0 PDSP Ki database
SST5 SSR5 Human Somatostatin A pKi 6.7 6.7 6.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database