nortriptyline [5840]



nortriptyline


SMILES CNCCC=C1c2ccccc2CCc2ccccc21
InChIKey PHVGLTMQBUFIQQ-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 3
Log P 3.826
Molecular weight (Da) 263.2
Stereochemistry info unspecified

Database connections

Model (Boltz2) 5-HT2A

Bioactivities

Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database
Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database

nortriptyline


Drug properties

Molecular type Lipid
Physiological/Surrogate Surrogate
Approved drug Yes

Distribution across phases (no. indications)

Phase I 1
Phase II 3
Phase III 2
Phase IV 1

Database connections

Model (Boltz2) 5-HT2A

Sankey plot

Drug Information

Target Disease
Gene Protein Receptor family Ligand type Class Name Phase ICD11 ATC Association score