NPC-349 [5854]
NPC-349
| SMILES | NC(N)=NCCC[C@@H](N)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)C(CCN=C(N)N)[C@](C(=O)O)(C(=O)CNC(=O)[C@@H]1C[C@@H](O)CN1)N(C(=O)[C@@H](N)Cc1cccs1)C(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cccs1 |
| InChIKey | MHBUKMPYIGAURU-WIDHDRDXSA-N |
| Sequence | RRXXGXSFXR |
Chemical Properties
| Hydrogen bond acceptors | 21 |
| Hydrogen bond donors | 17 |
| Rotatable bonds | 36 |
| Log P | -6.200 |
| Molecular weight (Da) | 1293.6 |
| Stereochemistry info | partial |
Database connections
| Model (AF2) | B2 |
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Protein | Gene | Species | Family | Class | Type | Min | Avg | Max | Database |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Protein | Gene | Species | Family | Class | Type | Min | Avg | Max | Database |
NPC-349
Drug properties
| Molecular type | Peptide |
| Physiological/Surrogate | Surrogate |
| Approved drug | No |
Distribution across phases (no. indications)
Phase I
0
Phase II
0
Phase III
0
Phase IV
0
Database connections
| Model (AF2) | B2 |