valsartan
SMILES | CCCCC(=O)N([C@H](C(=O)O)C(C)C)Cc1ccc(cc1)c1ccccc1c1nnn[nH]1 |
InChIKey | ACWBQPMHZXGDFX-QFIPXVFZSA-N |
Chemical properties
Hydrogen bond acceptors | 5 |
Hydrogen bond donors | 2 |
Rotatable bonds | 10 |
Molecular weight (Da) | 435.2 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | Yes |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
PAF | PTAFR | Guinea pig | Platelet-activating factor | A | pKi | 7.54 | 7.54 | 7.54 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
PAF | PTAFR | Human | Platelet-activating factor | A | pIC50 | 3.6 | 5.67 | 6.52 | Guide to Pharmacology |
PAF | PTAFR | Guinea pig | Platelet-activating factor | A | pIC50 | 7.14 | 7.14 | 7.14 | ChEMBL |