CHEMBL159929


SMILES O=C(c1ccc(F)cc1)C1CCN(CCC2CCc3occc3C2=O)CC1
InChIKey GYKDCMFZJCNANX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 369.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Rat 5-Hydroxytryptamine A pKd 6.63 6.63 6.63 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.46 6.46 6.47 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.11 7.35 7.58 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.14 6.14 6.14 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database