CHEMBL1771105


SMILES COc1ccc2c(c1)CCCN(CCCCN1CCN(c3ccccc3OC)CC1)C2=O
InChIKey OLFPBASVCZUWSQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 437.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Pig 5-Hydroxytryptamine A pKi 6.09 6.09 6.09 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.49 8.76 9.03 ChEMBL
D3 DRD3 Human Dopamine A pKi 9.57 9.57 9.57 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.52 8.52 8.52 ChEMBL
D1 DRD1 Pig Dopamine A pKi 5.68 5.68 5.68 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database