CHEMBL1771106


SMILES COc1ccccc1N1CCN(CCCCN2CCc3cc(F)ccc3C2=O)CC1
InChIKey ZAZPPOBRQFIKRC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 411.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Pig 5-Hydroxytryptamine A pKi 6.08 6.08 6.08 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.58 7.81 8.04 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.8 8.8 8.8 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.55 8.55 8.55 ChEMBL
D1 DRD1 Pig Dopamine A pKi 5.64 5.64 5.64 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database