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Agent/drug
Bioactivity

CLOPIDOGREL

SMILES	COC(=O)[C@H](c1ccccc1Cl)N1CCc2sccc2C1
InChIKey	GKTWGGQPFAXNFI-HNNXBMFYSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	0
Rotatable bonds	3
Molecular weight (Da)	321.1

Database connections

ChEMBL_compound_ids PubChem DrugBank PubChem GPCRdb

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

P2Y₁₂	P2Y12	Human	P2Y	A	pKi	8.16	8.16	8.16	Drug Central

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Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

P2Y₁₂	P2Y12	Human	P2Y	A	pIC50	5.62	5.62	5.62	ChEMBL

Showing 1 to 1 of 1 entry

CLOPIDOGREL

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	Yes

Clinical Trials

Phase I 1

Phase II 5

Phase III 13

Approved Yes

Database connections

ChEMBL_compound_ids PubChem DrugBank PubChem GPCRdb

Sankey plot

Drug Information

Search:

Target					Disease				Phase

Gene	Protein	Receptor family	Ligand type	Class	Indication name	ICD11	ATC	Association score	Phase	Approved

P2Y12	P2Y₁₂ receptor	P2Y receptors	Nucleotide receptors	Class A	Acute ST elevation myocardial infarction	BA41.0		0.595	4	Yes
P2Y12	P2Y₁₂ receptor	P2Y receptors	Nucleotide receptors	Class A	Acute ischaemic heart disease, unspecified	BA4Z		0.612	4	Yes
P2Y12	P2Y₁₂ receptor	P2Y receptors	Nucleotide receptors	Class A	Acute myocardial infarction, unspecified	BA41.Z		0.610	4	Yes
P2Y12	P2Y₁₂ receptor	P2Y receptors	Nucleotide receptors	Class A	Acute non-ST elevation myocardial infarction	BA41.1		0.260	4	Yes
P2Y12	P2Y₁₂ receptor	P2Y receptors	Nucleotide receptors	Class A	Angina pectoris, unspecified	BA40.Z		0.574	3	Yes
P2Y12	P2Y₁₂ receptor	P2Y receptors	Nucleotide receptors	Class A	Asthma	CA23		0.396	2	Yes
P2Y12	P2Y₁₂ receptor	P2Y receptors	Nucleotide receptors	Class A	Asymptomatic stenosis of intracranial or extracranial artery	BD55		0.386	3	Yes
P2Y12	P2Y₁₂ receptor	P2Y receptors	Nucleotide receptors	Class A	Atherosclerotic chronic arterial occlusive disease, unspecified	BD40.Z		0.412	3	Yes
P2Y12	P2Y₁₂ receptor	P2Y receptors	Nucleotide receptors	Class A	Atrial fibrillation, unspecified	BC81.3Z		0.589	3	Yes
P2Y12	P2Y₁₂ receptor	P2Y receptors	Nucleotide receptors	Class A	COVID-19	RA01		0.365	3	Yes
P2Y12	P2Y₁₂ receptor	P2Y receptors	Nucleotide receptors	Class A	Cerebral ischaemic stroke, unspecified	8B11.5Z		0.517	3	Yes
P2Y12	P2Y₁₂ receptor	P2Y receptors	Nucleotide receptors	Class A	Chronic arterial occlusive disease, unspecified	BD4Z		0.392	3	Yes
P2Y12	P2Y₁₂ receptor	P2Y receptors	Nucleotide receptors	Class A	Congenital supravalvar aortic stenosis	LA8A.3		0.561	3	Yes
P2Y12	P2Y₁₂ receptor	P2Y receptors	Nucleotide receptors	Class A	Diseases of arteries or arterioles, unspecified	BD5Z		0.483	4	Yes
P2Y12	P2Y₁₂ receptor	P2Y receptors	Nucleotide receptors	Class A	Diseases of the circulatory system, unspecified	BE2Z		0.441	3	Yes
P2Y12	P2Y₁₂ receptor	P2Y receptors	Nucleotide receptors	Class A	Gastrointestinal bleeding, unspecified	ME24.9Z		0.463	3	Yes
P2Y12	P2Y₁₂ receptor	P2Y receptors	Nucleotide receptors	Class A	Heart failure, unspecified	BD1Z		0.261	3	Yes
P2Y12	P2Y₁₂ receptor	P2Y receptors	Nucleotide receptors	Class A	Malignant neoplasms of ill-defined sites	2D42		0.037	1	Yes
P2Y12	P2Y₁₂ receptor	P2Y receptors	Nucleotide receptors	Class A	Neoplasms of unknown behaviour of breast	2F95		0.046	2	Yes
P2Y12	P2Y₁₂ receptor	P2Y receptors	Nucleotide receptors	Class A	Polycythaemia vera	2A20.4		0.077	2	Yes

Showing 1 to 20 of 26 entries

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CLOPIDOGREL

CLOPIDOGREL

Chemical Properties

Database connections

Bioactivities

CLOPIDOGREL

Drug properties

Clinical Trials

Database connections

Sankey plot

Drug Information