PF-07054894 [6247]



PF-07054894


SMILES Cc1cn(C)nc1[C@H](Nc1c(Nc2ccnc(C(=O)N(C)C)c2O)c(=O)c1=O)C1(C)CCCC1
InChIKey WZBSYWCLIMRAHO-QFIPXVFZSA-N

Chemical Properties

Hydrogen bond acceptors 9
Hydrogen bond donors 3
Rotatable bonds 7
Log P 2.604
Molecular weight (Da) 466.2
Stereochemistry info full

Database connections

Structure pdb 9PEE

Bioactivities

Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database
Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database

PF-07054894


Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Distribution across phases (no. indications)

Phase I 1
Phase II 0
Phase III 0
Phase IV 0

Database connections

Structure pdb 9PEE

Sankey plot

Drug Information

Target Disease
Gene Protein Receptor family Ligand type Class Name Phase ICD11 ATC Association score