PGI2 [6282]



PGI2


SMILES CCCCC[C@H](O)/C=C/[C@@H]1[C@H]2C/C(=C/CCCC(=O)O)O[C@H]2C[C@H]1O
InChIKey KAQKFAOMNZTLHT-OZUDYXHBSA-N

Chemical Properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 10
Log P 3.408
Molecular weight (Da) 352.2
Stereochemistry info full

Database connections

Model (RFAA) FP TP EP2 EP3
Model (Boltz2) IP
GPCRdb related ligands

Bioactivities

Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database
Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database

PGI2


Drug properties

Molecular type Small molecule
Physiological/Surrogate Endogenous
Approved drug Yes

Distribution across phases (no. indications)

Phase I 2
Phase II 6
Phase III 0
Phase IV 2

Database connections

Model (RFAA) FP TP EP2 EP3
Model (Boltz2) IP

Sankey plot

Drug Information

Target Disease
Gene Protein Receptor family Ligand type Class Name Phase ICD11 ATC Association score