CPPZ


SMILES Fc1ccc(c(c1)Cl)N1CCN(CC1)C(=O)COCc1ccncc1
InChIKey XNOMHUDLVRWWLV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 363.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pKi 5.51 5.51 5.51 Guide to Pharmacology
mGlu5 GRM5 Human Metabotropic glutamate C pKi 5.62 5.62 5.62 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Human Metabotropic glutamate C pEC50 6.3 6.3 6.3 Guide to Pharmacology
mGlu5 GRM5 Human Metabotropic glutamate C pEC50 6.26 6.26 6.26 ChEMBL