CPPZ
SMILES | Fc1ccc(c(c1)Cl)N1CCN(CC1)C(=O)COCc1ccncc1 |
InChIKey | XNOMHUDLVRWWLV-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 4 |
Hydrogen bond donors | 0 |
Rotatable bonds | 5 |
Molecular weight (Da) | 363.1 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
mGlu5 | GRM5 | Rat | Metabotropic glutamate | C | pKi | 5.51 | 5.51 | 5.51 | Guide to Pharmacology |
mGlu5 | GRM5 | Human | Metabotropic glutamate | C | pKi | 5.62 | 5.62 | 5.62 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
mGlu5 | GRM5 | Human | Metabotropic glutamate | C | pEC50 | 6.3 | 6.3 | 6.3 | Guide to Pharmacology |
mGlu5 | GRM5 | Human | Metabotropic glutamate | C | pEC50 | 6.26 | 6.26 | 6.26 | ChEMBL |