compound 29b [PMID: 20809633]


SMILES C#Cc1cc(F)cc(c1)N1CCCc2c(C1)nc(o2)c1ccccn1
InChIKey MVXAKOGJWVQPKC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 2
Molecular weight (Da) 333.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.77 6.77 6.77 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 9.27 9.29 9.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database