compound 27 [PMID: 20598884]


SMILES N#Cc1cc(F)cc(c1)C(=O)Nc1cccc(c1)Cl
InChIKey FNDUFJARTKDXEF-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 274.0

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pKd 7.3 7.3 7.3 ChEMBL
H4 HRH4 Human Histamine A pKi 7.1 7.1 7.1 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pEC50 6.33 6.33 6.33 ChEMBL