Bms-986235


SMILES COc1cc(F)c(c(c1)F)[C@@H]1CNC(=O)[C@H]1NC(=O)Nc1ccccc1
InChIKey FJZNNKJZHQFMCK-LRDDRELGSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 4
Molecular weight (Da) 361.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
FPR1 FPR1 Human Formylpeptide A pEC50 6.4 6.4 6.4 Guide to Pharmacology
FPR1 FPR1 Mouse Formylpeptide A pEC50 6.3 6.3 6.3 Guide to Pharmacology
FPR2/ALX FPR2 Human Formylpeptide A pEC50 8.3 8.3 8.3 Guide to Pharmacology
FPR2/ALX FPR2 Mouse Formylpeptide A pEC50 9.3 9.3 9.3 Guide to Pharmacology
FPR1 FPR1 Mouse Formylpeptide A pEC50 6.3 6.3 6.3 ChEMBL
FPR2/ALX FPR2 Mouse Formylpeptide A pEC50 8.47 8.89 9.3 ChEMBL
FPR1 FPR1 Human Formylpeptide A pEC50 5.55 5.97 6.4 ChEMBL
FPR2/ALX FPR2 Human Formylpeptide A pEC50 6.89 8.19 9.39 ChEMBL
FPR2/ALX FPR2 Human Formylpeptide A pIC50 7.24 7.24 7.24 ChEMBL