NPC 17731


SMILES None
InChIKey WYWZCALINPVKJW-KOCZGPIPSA-N
Sequence RRPXGFSXXR

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Peptide
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu2 GRM2 Human Metabotropic glutamate C pKi 7.22 7.22 7.22 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pKd 6.72 6.72 6.72 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu2 GRM2 Human Metabotropic glutamate C pEC50 7.0 7.0 7.0 Guide to Pharmacology
mGlu2 GRM2 Human Metabotropic glutamate C pEC50 7.03 7.29 7.56 ChEMBL
mGlu2 GRM2 Rat Metabotropic glutamate C pEC50 6.36 6.4 6.42 ChEMBL