PHENYLTOLOXAMINE


SMILES CN(C)CCOc1ccccc1Cc1ccccc1
InChIKey IZRPKIZLIFYYKR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 255.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D5 DRD5 Human Dopamine A pKi 6.38 6.38 6.38 ChEMBL
H1 HRH1 Human Histamine A pKi 7.9 7.9 7.9 ChEMBL
D1 DRD1 Human Dopamine A pKi 6.46 6.46 6.46 ChEMBL
D4 DRD4 Human Dopamine A pKi 5.56 5.56 5.56 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.56 5.56 5.56 ChEMBL
D1 DRD1 Human Dopamine A pKi 8.19 8.19 8.19 Drug Central
D2 DRD2 Human Dopamine A pKi 8.25 8.25 8.25 Drug Central
D4 DRD4 Human Dopamine A pKi 8.25 8.25 8.25 Drug Central
D5 DRD5 Human Dopamine A pKi 8.2 8.2 8.2 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database