CHEMBL1739922
SMILES | Cc1nn(C)c2nc(N(C)CCN(C)C)c(C(=O)NC(=O)Nc3cccc(OC(C)C)c3)cc12 |
InChIKey | MFORNGKVWCJAME-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 8 |
Hydrogen bond donors | 2 |
Rotatable bonds | 8 |
Molecular weight (Da) | 467.3 |
Drug properties
Molecular type | Small molecule |
Physiological/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
CCR2 | CCR2 | Rat | Chemokine | A | pIC50 | 5.0 | 5.0 | 5.0 | ChEMBL |
CCR2 | CCR2 | Mouse | Chemokine | A | pIC50 | 4.92 | 4.92 | 4.92 | ChEMBL |
CCR2 | CCR2 | Human | Chemokine | A | pIC50 | 6.7 | 6.97 | 7.1 | ChEMBL |
CCR5 | CCR5 | Human | Chemokine | A | pIC50 | 6.4 | 6.4 | 6.4 | ChEMBL |