Chembl1922270

Chemical Properties

SMILES C[C@H]1c2c([nH]c3ccc(C(F)(F)F)cc23)C[C@H]2CCN(CCCC3CCOCC3)C[C@@H]21
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight 434.3

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey VGWOOKCYUNUQRH-HGHGUNKESA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MCH1 MCHR1 Rat Melanin-concentrating hormone A pIC50 8.4 8.4 8.4 ChEMBL
MCH1 MCHR1 Human Melanin-concentrating hormone A pIC50 8.22 8.94 9.3 ChEMBL