BMS-986235
SMILES | COc1cc(F)c(c(c1)F)[C@@H]1CNC(=O)[C@H]1NC(=O)Nc1ccccc1 |
InChIKey | FJZNNKJZHQFMCK-LRDDRELGSA-N |
Chemical properties
Hydrogen bond acceptors | 3 |
Hydrogen bond donors | 3 |
Rotatable bonds | 4 |
Molecular weight (Da) | 361.1 |
Drug properties
Molecular type | Small molecule |
Physiological/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
FPR1 | FPR1 | Human | Formylpeptide | A | pEC50 | 6.4 | 6.4 | 6.4 | Guide to Pharmacology |
FPR2/ALX | FPR2 | Human | Formylpeptide | A | pEC50 | 8.3 | 8.3 | 8.3 | Guide to Pharmacology |
FPR1 | FPR1 | Mouse | Formylpeptide | A | pEC50 | 6.3 | 6.3 | 6.3 | Guide to Pharmacology |
FPR2/ALX | FPR2 | Mouse | Formylpeptide | A | pEC50 | 9.3 | 9.3 | 9.3 | Guide to Pharmacology |
FPR2/ALX | FPR2 | Human | Formylpeptide | A | pIC50 | 7.24 | 7.68 | 8.12 | ChEMBL |
FPR2/ALX | FPR2 | Human | Formylpeptide | A | pEC50 | 5.9 | 7.76 | 9.39 | ChEMBL |
FPR1 | FPR1 | Human | Formylpeptide | A | pEC50 | 5.55 | 6.12 | 6.4 | ChEMBL |
FPR1 | FPR1 | Mouse | Formylpeptide | A | pEC50 | 6.3 | 7.76 | 9.22 | ChEMBL |
FPR2/ALX | FPR2 | Mouse | Formylpeptide | A | pEC50 | 6.42 | 8.06 | 9.3 | ChEMBL |