CHEMBL1923415


SMILES Oc1cc(CN2CCN(c3ccc4c(c3)OCCO4)CC2)ccc1F
InChIKey SXICCGPFVRVNMD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 344.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Pig 5-Hydroxytryptamine A pKi 5.64 5.64 5.64 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.14 8.14 8.14 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.38 5.38 5.38 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.05 5.13 5.21 ChEMBL
D1 DRD1 Pig Dopamine A pKi 4.82 4.82 4.82 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database