5-fluorotryptamine


SMILES NCCc1c[nH]c2c1cc(F)cc2
InChIKey ZKIORVIXEWIOGB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 1
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 178.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1E 5HT1E Human 5-Hydroxytryptamine A pKi 6.3 6.3 6.3 Guide to Pharmacology
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.96 7.96 7.96 PDSP Ki database
5-HT2B 5HT2B Rat 5-Hydroxytryptamine A pKi 8.25 8.25 8.25 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pEC50 5.65 5.65 5.65 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pEC50 8.58 8.58 8.58 ChEMBL