Chembl1940412

Chemical Properties

SMILES Fc1ccc(OCCCN2CCN(c3ccccc3)CC2)cc1
Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight 314.2

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey GUOQPFNLBAXWIZ-UHFFFAOYSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 8.13 8.13 8.13 ChEMBL
H1 HRH1 Human Histamine A pKi 7.2 7.2 7.2 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.62 7.62 7.62 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.24 7.24 7.24 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.68 6.68 6.68 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.43 7.43 7.43 ChEMBL