Chembl1940417

Chemical Properties

SMILES Fc1ccc(OCCCN2CCN(c3ncccn3)CC2)cc1
Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight 316.2

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey FGFQEEFTBWHCLW-UHFFFAOYSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 8.38 8.38 8.38 ChEMBL
D1 DRD1 Human Dopamine A pKi 6.59 6.59 6.59 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.64 7.64 7.64 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.64 7.64 7.64 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.11 6.11 6.11 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.2 6.2 6.2 ChEMBL