Chembl194051
Chemical Properties
| SMILES | O=C(Nc1cc(-c2ccccc2)nn1-c1ccccc1)c1cccc(F)c1 |
| Hydrogen bond acceptors | 3 |
| Hydrogen bond donors | 1 |
| Rotatable bonds | 4 |
| Molecular weight | 357.1 |
Drug Properties
| Type | Small molecule |
| Endogenous | No |
| Approved | No |
| InChIKey | QZORXXWBXJAPEC-UHFFFAOYSA-N |
Bioactivity
| Receptor | Experimental Data | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| mGlu5 | GRM5 | Rat | Metabotropic glutamate | C | pEC50 | 7.19 | 7.19 | 7.19 | ChEMBL |
| mGlu5 | GRM5 | Human | Metabotropic glutamate | C | pEC50 | 7.7 | 7.7 | 7.7 | ChEMBL |