CHEMBL1940416


SMILES Fc1ccc(SCCCN2CCN(c3ncccn3)CC2)cc1
InChIKey WRSUPAJSUHYUKP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 332.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 7.68 7.68 7.68 ChEMBL
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 5.05 5.05 5.05 ChEMBL
D5 DRD5 Human Dopamine A pKi 5.86 5.86 5.86 ChEMBL
D1 DRD1 Human Dopamine A pKi 6.3 6.3 6.3 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.03 7.03 7.03 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.57 7.57 7.57 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.17 7.17 7.17 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.37 6.37 6.37 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database