SPIROTRAMINE


SMILES CN(CCCCCCCCN(C)CCCCCCN1CCC2(CC1)OC(=O)C(c1ccccc1)(c1ccccc1)O2)CCCCCCN1CCC2(CC1)OC(=O)C(c1ccccc1)(c1ccccc1)O2
InChIKey VWEQLDJRUYNWOE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 10
Hydrogen bond donors 0
Rotatable bonds 27
Molecular weight (Da) 954.6

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M4 ACM4 Rat Acetylcholine (muscarinic) A pKi 6.27 6.27 6.27 ChEMBL
M3 ACM3 Rat Acetylcholine (muscarinic) A pKi 6.01 6.01 6.01 ChEMBL
M2 ACM2 Rat Acetylcholine (muscarinic) A pKi 6.2 6.2 6.2 ChEMBL
M1 ACM1 Rat Acetylcholine (muscarinic) A pKi 7.88 7.88 7.88 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database