[Ac-His1]PACAP-27
SMILES | None |
InChIKey | GDQXRMJXFNQXMJ-QYHUGZLJSA-N |
Sequence | HSDGIFTDSYSRYRKQMAVKKYLAAVL |
Chemical properties
Hydrogen bond acceptors | None |
Hydrogen bond donors | None |
Rotatable bonds | None |
Molecular weight (Da) |
Drug properties
Molecular type | Peptide |
Physiological/Surrogate | Surrogate |
Approved drug | No |
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
PAC1 | PACR | Rat | VIP and PACAP | B1 | pKi | 8.15 | 8.15 | 8.15 | Guide to Pharmacology |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
PAC1 | PACR | Human | VIP and PACAP | B1 | pIC50 | 8.52 | 8.52 | 8.52 | ChEMBL |
PAC1 | PACR | Human | VIP and PACAP | B1 | pEC50 | 9.89 | 9.89 | 9.89 | ChEMBL |
VPAC1 | VIPR1 | Human | VIP and PACAP | B1 | pIC50 | 7.92 | 7.92 | 7.92 | ChEMBL |
VPAC1 | VIPR1 | Human | VIP and PACAP | B1 | pEC50 | 9.22 | 9.22 | 9.22 | ChEMBL |
VPAC2 | VIPR2 | Human | VIP and PACAP | B1 | pIC50 | 7.89 | 7.89 | 7.89 | ChEMBL |
VPAC2 | VIPR2 | Human | VIP and PACAP | B1 | pEC50 | 10.06 | 10.06 | 10.06 | ChEMBL |