ACTH-(1-24)
| SMILES | None |
| InChIKey | ZOEFCCMDUURGSE-SQKVDDBVSA-N |
| Sequence | SYSMEHFRWGKPVGKKRRPVKVYP |
Chemical properties
| Hydrogen bond acceptors | None |
| Hydrogen bond donors | None |
| Rotatable bonds | None |
| Molecular weight (Da) |
Drug properties
| Molecular type | Peptide |
| Physiological/Surrogate | Surrogate |
| Approved drug | Yes |
Database connections
| Ligand site mutations | MC4 |
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| MC2 | ACTHR | Mouse | Melanocortin | A | pKd | 9.1 | 9.1 | 9.1 | Guide to Pharmacology |
| MC2 | ACTHR | Human | Melanocortin | A | pKi | 8.08 | 8.08 | 8.08 | Drug Central |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| MC4 | MC4R | Human | Melanocortin | A | pEC50 | 8.04 | 8.04 | 8.04 | Drug Central |
| MC4 | MC4R | Human | Melanocortin | A | pEC50 | 9.19 | 9.19 | 9.19 | ChEMBL |