CHEMBL1956193


SMILES CC(Oc1ccccc1C(F)(F)F)C1=NCCN1
InChIKey BFKLSSIIDDEGQB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 258.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 5.79 5.79 5.79 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 6.01 6.01 6.01 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 6.74 6.74 6.74 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pEC50 6.62 6.62 6.62 ChEMBL
α2C ADA2C Human Adrenoceptors A pEC50 6.1 6.1 6.1 ChEMBL