bradykinin


SMILES None
InChIKey QXZGBUJJYSLZLT-FDISYFBBSA-N
Sequence RPPGFSPFR

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Peptide
Endogenous/Surrogate Endogenous
Approved drug Yes

Database connections

Structure pdb 7F6H 7F2O

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
B1 BKRB1 Human Bradykinin A pKi 4.0 4.0 4.0 Guide to Pharmacology
B1 BKRB1 Mouse Bradykinin A pKi 6.7 6.7 6.7 Guide to Pharmacology
B2 BKRB2 Mouse Bradykinin A pKd 9.4 9.4 9.4 Guide to Pharmacology
B1 BKRB1 Rat Bradykinin A pKi 5.1 5.2 5.3 Guide to Pharmacology
B2 BKRB2 Human Bradykinin A pKi 8.96 9.49 10.19 ChEMBL
B2 BKRB2 Rat Bradykinin A pKi 9.34 9.34 9.34 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
B2 BKRB2 Human Bradykinin A pIC50 7.0 8.15 9.3 Guide to Pharmacology
B2 BKRB2 Mouse Bradykinin A pIC50 9.3 9.3 9.3 Guide to Pharmacology
Olfactory 51E2 O51E2 Human Olfactory A pEC50 8.89 8.89 8.89 ChEMBL
B2 BKRB2 Human Bradykinin A pIC50 8.74 8.74 8.74 ChEMBL
B2 BKRB2 Human Bradykinin A pEC50 10.31 10.31 10.31 ChEMBL