α-neoendorphin
SMILES | None |
InChIKey | KZTDMJBCZSGHOG-XJIZABAQSA-N |
Sequence | YGGFLRKYPK |
Chemical properties
Hydrogen bond acceptors | None |
Hydrogen bond donors | None |
Rotatable bonds | None |
Molecular weight (Da) |
Drug properties
Molecular type | Peptide |
Physiological/Surrogate | Endogenous |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
κ | OPRK | Rat | Opioid | A | pKi | 8.9 | 9.45 | 10.0 | Guide to Pharmacology |
δ | OPRD | Human | Opioid | A | pKi | 8.77 | 8.77 | 8.77 | ChEMBL |
κ | OPRK | Human | Opioid | A | pKi | 8.62 | 8.62 | 8.62 | ChEMBL |
κ | OPRK | Human | Opioid | A | pKi | 8.3 | 9.25 | 10.2 | Guide to Pharmacology |
μ | OPRM | Human | Opioid | A | pKi | 8.14 | 8.14 | 8.14 | ChEMBL |
μ | OPRM | Mouse | Opioid | A | pKi | 8.44 | 8.55 | 8.67 | PDSP Ki database |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
δ | OPRD | Mouse | Opioid | A | pIC50 | 8.0 | 8.0 | 8.0 | Guide to Pharmacology |
κ | OPRK | Mouse | Opioid | A | pIC50 | 10.0 | 10.0 | 10.0 | Guide to Pharmacology |