AMG7703


SMILES CC([C@H](C(=O)Nc1nccs1)c1ccc(cc1)Cl)C
InChIKey AZYDQCGCBQYFSE-LBPRGKRZSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 294.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
FFA2 FFAR2 Human Free fatty acid A pEC50 5.9 6.12 6.35 Guide to Pharmacology
FFA2 FFAR2 Mouse Free fatty acid A pEC50 6.8 6.8 6.8 ChEMBL
FFA2 FFAR2 Human Free fatty acid A pEC50 6.38 6.69 7.0 ChEMBL
FFA2 FFAR2 Human Free fatty acid A pIC50 6.16 6.16 6.16 ChEMBL