mesoridazine


SMILES CN1CCCCC1CCN1c2ccccc2Sc2c1cc(cc2)S(=O)C
InChIKey SLVMESMUVMCQIY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 386.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β1 ADRB1 Human Adrenoceptors A pKi 7.5 7.5 7.5 ChEMBL
β3 ADRB3 Human Adrenoceptors A pKi 6.6 6.6 6.6 ChEMBL
β2 ADRB2 Human Adrenoceptors A pKi 9.52 9.52 9.52 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β1 ADRB1 Human Adrenoceptors A pEC50 6.51 6.51 6.51 ChEMBL
β3 ADRB3 Human Adrenoceptors A pEC50 6.42 6.42 6.42 ChEMBL
β2 ADRB2 Human Adrenoceptors A pIC50 7.5 7.5 7.5 ChEMBL