mesoridazine
| SMILES | CN1CCCCC1CCN1c2ccccc2Sc2c1cc(cc2)S(=O)C |
| InChIKey | SLVMESMUVMCQIY-UHFFFAOYSA-N |
Chemical properties
| Hydrogen bond acceptors | 4 |
| Hydrogen bond donors | 0 |
| Rotatable bonds | 4 |
| Molecular weight (Da) | 386.1 |
Drug properties
| Molecular type | Small molecule |
| Physiological/Surrogate | Surrogate |
| Approved drug | Yes |
Database connections
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
GTP
| Uniprot
| Species
| Family
| Class
| Type
| Min | Avg | Max | Database
|
| 5-HT1A | 5HT1A | Human | 5-Hydroxytryptamine | A | pKi | 8.16 | 8.16 | 8.16 | Drug Central |
| 5-HT1A | 5HT1A | Human | 5-Hydroxytryptamine | A | pKi | 6.3 | 6.3 | 6.3 | PDSP Ki database |
| 5-HT1A | 5HT1A | Human | 5-Hydroxytryptamine | A | pKi | 6.98 | 6.98 | 6.98 | Guide to Pharmacology |
| 5-HT2A | 5HT2A | Human | 5-Hydroxytryptamine | A | pKi | 7.26 | 7.26 | 7.26 | Guide to Pharmacology |
| 5-HT2A | 5HT2A | Human | 5-Hydroxytryptamine | A | pKi | 8.09 | 8.09 | 8.09 | Drug Central |
| 5-HT2A | 5HT2A | Human | 5-Hydroxytryptamine | A | pKi | 7.93 | 8.15 | 8.32 | PDSP Ki database |
| 5-HT2A | 5HT2A | Rat | 5-Hydroxytryptamine | A | pKi | 8.2 | 8.2 | 8.2 | PDSP Ki database |
| 5-HT2C | 5HT2C | Human | 5-Hydroxytryptamine | A | pKi | 6.8 | 6.8 | 6.8 | PDSP Ki database |
| 5-HT2C | 5HT2C | Human | 5-Hydroxytryptamine | A | pKi | 8.17 | 8.17 | 8.17 | Drug Central |
| 5-HT2C | 5HT2C | Human | 5-Hydroxytryptamine | A | pKi | 6.39 | 6.39 | 6.39 | Guide to Pharmacology |
| 5-HT2C | 5HT2C | Rat | 5-Hydroxytryptamine | A | pKi | 6.8 | 7.0 | 7.1 | PDSP Ki database |
| 5-HT6 | 5HT6R | Human | 5-Hydroxytryptamine | A | pKi | 8.19 | 8.19 | 8.19 | Drug Central |
| 5-HT6 | 5HT6R | Human | 5-Hydroxytryptamine | A | pKi | 6.42 | 6.42 | 6.42 | PDSP Ki database |
| 5-HT6 | 5HT6R | Rat | 5-Hydroxytryptamine | A | pKi | 6.8 | 6.8 | 6.8 | PDSP Ki database |
| 5-HT7 | 5HT7R | Human | 5-Hydroxytryptamine | A | pKi | 7.14 | 7.14 | 7.14 | PDSP Ki database |
| 5-HT7 | 5HT7R | Rat | 5-Hydroxytryptamine | A | pKi | 7.14 | 7.14 | 7.14 | PDSP Ki database |
| D1 | DRD1 | Human | Dopamine | A | pKi | 8.16 | 8.16 | 8.16 | Drug Central |
| D1 | DRD1 | Human | Dopamine | A | pKi | 6.99 | 6.99 | 6.99 | Guide to Pharmacology |
| D2 | DRD2 | Human | Dopamine | A | pKi | 8.11 | 8.11 | 8.11 | Drug Central |
| D2 | DRD2 | Human | Dopamine | A | pKi | 7.72 | 7.94 | 8.37 | PDSP Ki database |
| D2 | DRD2 | Human | Dopamine | A | pKi | 8.66 | 8.66 | 8.66 | Guide to Pharmacology |
| D2 | DRD2 | Rat | Dopamine | A | pKi | 8.1 | 8.2 | 8.3 | PDSP Ki database |
| D3 | DRD3 | Human | Dopamine | A | pKi | 8.07 | 8.07 | 8.07 | Drug Central |
| D3 | DRD3 | Human | Dopamine | A | pKi | 8.59 | 8.59 | 8.59 | PDSP Ki database |
| D3 | DRD3 | Human | Dopamine | A | pKi | 7.64 | 7.64 | 7.64 | Guide to Pharmacology |
| D4 | DRD4 | Human | Dopamine | A | pKi | 8.09 | 8.09 | 8.09 | Drug Central |
| D4 | DRD4 | Human | Dopamine | A | pKi | 8.04 | 8.04 | 8.04 | PDSP Ki database |
| D4 | DRD4 | Rat | Dopamine | A | pKi | 7.87 | 7.87 | 7.87 | PDSP Ki database |
| H1 | HRH1 | Human | Histamine | A | pKi | 8.06 | 8.06 | 8.06 | Drug Central |
| H1 | HRH1 | Human | Histamine | A | pKi | 8.74 | 8.74 | 8.74 | PDSP Ki database |
| M1 | ACM1 | Human | Acetylcholine (muscarinic) | A | pKi | 8.1 | 8.1 | 8.1 | Drug Central |
| M1 | ACM1 | Human | Acetylcholine (muscarinic) | A | pKi | 7.8 | 7.9 | 8.0 | PDSP Ki database |
| M2 | ACM2 | Human | Acetylcholine (muscarinic) | A | pKi | 8.11 | 8.11 | 8.11 | Drug Central |
| M2 | ACM2 | Human | Acetylcholine (muscarinic) | A | pKi | 7.17 | 7.5 | 7.82 | PDSP Ki database |
| M3 | ACM3 | Human | Acetylcholine (muscarinic) | A | pKi | 8.15 | 8.15 | 8.15 | Drug Central |
| M3 | ACM3 | Human | Acetylcholine (muscarinic) | A | pKi | 7.05 | 7.05 | 7.05 | PDSP Ki database |
| M3 | ACM3 | Rat | Acetylcholine (muscarinic) | A | pKi | 7.05 | 7.05 | 7.05 | PDSP Ki database |
| M4 | ACM4 | Human | Acetylcholine (muscarinic) | A | pKi | 8.11 | 8.11 | 8.11 | Drug Central |
| M4 | ACM4 | Human | Acetylcholine (muscarinic) | A | pKi | 7.72 | 7.72 | 7.72 | PDSP Ki database |
| M5 | ACM5 | Human | Acetylcholine (muscarinic) | A | pKi | 8.14 | 8.14 | 8.14 | Drug Central |
| M5 | ACM5 | Human | Acetylcholine (muscarinic) | A | pKi | 7.22 | 7.22 | 7.22 | PDSP Ki database |
Showing 1 to 41 of 41 entries
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
GTP
| Uniprot
| Species
| Family
| Class
| Type
| Min | Avg | Max | Database
|
| No data available in table | |||||||||
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