HU-210


SMILES CCCCCCC(c1cc(O)c2c(c1)OC([C@H]1[C@H]2CC(=CC1)CO)(C)C)(C)C
InChIKey SSQJFGMEZBFMNV-WOJBJXKFSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 7
Molecular weight (Da) 386.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GnRH1 GNRHR Human Gonadotrophin-releasing hormone A pKi 9.4 9.7 10.0 Guide to Pharmacology
GnRH1 GNRHR Human Gonadotrophin-releasing hormone A pKd 9.52 9.96 10.4 Guide to Pharmacology
LH LSHR Human Glycoprotein hormone A pKd 8.07 8.07 8.07 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GnRH1 GNRHR Human Gonadotrophin-releasing hormone A pEC50 10.52 10.52 10.52 Guide to Pharmacology
GnRH1 GNRHR Mouse Gonadotrophin-releasing hormone A pEC50 9.34 9.7 10.05 Guide to Pharmacology
GnRH1 GNRHR Human Gonadotrophin-releasing hormone A pEC50 7.98 7.98 7.98 Drug Central
GnRH1 GNRHR Mouse Gonadotrophin-releasing hormone A pEC50 8.0 8.0 8.0 Drug Central