vilanterol


SMILES OCc1cc(ccc1O)[C@H](CNCCCCCCOCCOCc1c(Cl)cccc1Cl)O
InChIKey DAFYYTQWSAWIGS-DEOSSOPVSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 4
Rotatable bonds 16
Molecular weight (Da) 485.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 6.34 6.34 6.34 ChEMBL
D4 DRD4 Human Dopamine A pIC50 5.73 5.73 5.73 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pIC50 6.93 6.93 6.93 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pIC50 5.85 5.85 5.85 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pIC50 6.22 6.22 6.22 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pIC50 6.52 6.52 6.52 ChEMBL
D3 DRD3 Human Dopamine A pIC50 6.48 6.48 6.48 ChEMBL
D2 DRD2 Human Dopamine A pIC50 5.97 5.97 5.97 ChEMBL