SULINDAC SULFIDE


SMILES CSc1ccc(/C=C2/C(C)=C(CC(=O)O)c3cc(F)ccc32)cc1
InChIKey LFWHFZJPXXOYNR-MFOYZWKCSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 340.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CysLT1 CLTR1 Human Leukotriene A pKi 4.83 4.83 4.83 ChEMBL
DP2 PD2R2 Human Prostanoid A pKi 5.46 5.46 5.46 ChEMBL
D1 DRD1 Human Dopamine A pKi 4.86 4.86 4.86 ChEMBL
A3 AA3R Human Adenosine A pKi 5.39 5.39 5.39 ChEMBL
μ OPRM Human Opioid A pKi 4.86 4.86 4.86 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CysLT1 CLTR1 Human Leukotriene A pIC50 4.53 4.53 4.53 ChEMBL
D1 DRD1 Human Dopamine A pIC50 4.56 4.56 4.56 ChEMBL
A3 AA3R Human Adenosine A pIC50 5.14 5.14 5.14 ChEMBL
μ OPRM Human Opioid A pIC50 4.47 4.47 4.47 ChEMBL