bradykinin
SMILES | None |
InChIKey | QXZGBUJJYSLZLT-FDISYFBBSA-N |
Sequence | RPPGFSPFR |
Chemical properties
Hydrogen bond acceptors | None |
Hydrogen bond donors | None |
Rotatable bonds | None |
Molecular weight (Da) |
Drug properties
Molecular type | Peptide |
Physiological/Surrogate | Endogenous |
Approved drug | Yes |
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
B1 | BKRB1 | Mouse | Bradykinin | A | pKi | 6.7 | 6.7 | 6.7 | Guide to Pharmacology |
B1 | BKRB1 | Rat | Bradykinin | A | pKi | 5.1 | 5.2 | 5.3 | Guide to Pharmacology |
B2 | BKRB2 | Mouse | Bradykinin | A | pKd | 9.4 | 9.4 | 9.4 | Guide to Pharmacology |
B1 | BKRB1 | Human | Bradykinin | A | pKi | 4.0 | 4.0 | 4.0 | Guide to Pharmacology |
B2 | BKRB2 | Human | Bradykinin | A | pKi | 8.96 | 9.49 | 10.19 | ChEMBL |
B2 | BKRB2 | Rat | Bradykinin | A | pKi | 9.34 | 9.34 | 9.34 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
B2 | BKRB2 | Human | Bradykinin | A | pIC50 | 7.0 | 8.15 | 9.3 | Guide to Pharmacology |
B2 | BKRB2 | Mouse | Bradykinin | A | pIC50 | 9.3 | 9.3 | 9.3 | Guide to Pharmacology |
OR51E2 | O51E2 | Human | Odorant family 51 | O1 | pEC50 | 8.89 | 8.89 | 8.89 | ChEMBL |
B2 | BKRB2 | Human | Bradykinin | A | pIC50 | 8.74 | 8.74 | 8.74 | ChEMBL |
B2 | BKRB2 | Human | Bradykinin | A | pEC50 | 10.31 | 10.31 | 10.31 | ChEMBL |