buserelin
| SMILES | None |
| InChIKey | CUWODFFVMXJOKD-UVLQAERKSA-N |
| Sequence | XHWSYSLRP |
Chemical properties
| Hydrogen bond acceptors | None |
| Hydrogen bond donors | None |
| Rotatable bonds | None |
| Molecular weight (Da) |
Drug properties
| Molecular type | Peptide |
| Physiological/Surrogate | Surrogate |
| Approved drug | Yes |
Database connections
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| GnRH1 | GNRHR | Human | Gonadotrophin-releasing hormone | A | pKd | 9.52 | 9.96 | 10.4 | Guide to Pharmacology |
| GnRH1 | GNRHR | Human | Gonadotrophin-releasing hormone | A | pKi | 9.4 | 9.7 | 10.0 | Guide to Pharmacology |
| LH | LSHR | Human | Glycoprotein hormone | A | pKd | 8.07 | 8.07 | 8.07 | Drug Central |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| GnRH1 | GNRHR | Human | Gonadotrophin-releasing hormone | A | pEC50 | 10.52 | 10.52 | 10.52 | Guide to Pharmacology |
| GnRH1 | GNRHR | Mouse | Gonadotrophin-releasing hormone | A | pEC50 | 9.34 | 9.7 | 10.05 | Guide to Pharmacology |
| GnRH1 | GNRHR | Mouse | Gonadotrophin-releasing hormone | A | pEC50 | 8.0 | 8.0 | 8.0 | Drug Central |
| GnRH1 | GNRHR | Human | Gonadotrophin-releasing hormone | A | pEC50 | 7.98 | 7.98 | 7.98 | Drug Central |