CHEMBL1922614


SMILES CNc1nn2c(N)cc(C)nc2c1S(=O)(=O)c1ccccc1
InChIKey UKQMQTGGUNTZKM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 317.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKd 9.3 9.3 9.3 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 9.52 9.52 9.52 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT6 5HT6R Human 5-Hydroxytryptamine A pIC50 7.92 8.72 9.53 ChEMBL