CCK-8
SMILES | None |
InChIKey | IZTQOLKUZKXIRV-YRVFCXMDSA-N |
Sequence | DYMGWMDF |
Chemical properties
Hydrogen bond acceptors | None |
Hydrogen bond donors | None |
Rotatable bonds | None |
Molecular weight (Da) |
Drug properties
Molecular type | Peptide |
Physiological/Surrogate | Endogenous |
Approved drug | Yes |
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
CCK2 | GASR | Rat | Cholecystokinin | A | pKi | 8.55 | 9.15 | 9.39 | ChEMBL |
CCK1 | CCKAR | Rat | Cholecystokinin | A | pKi | 8.06 | 9.36 | 10.05 | ChEMBL |
CCK1 | CCKAR | Human | Cholecystokinin | A | pKi | 9.55 | 9.55 | 9.55 | ChEMBL |
CCK2 | GASR | Rat | Cholecystokinin | A | pKi | 9.28 | 9.51 | 10.0 | PDSP Ki database |
CCK2 | GASR | Human | Cholecystokinin | A | pKi | 8.88 | 8.88 | 8.88 | PDSP Ki database |
CCK1 | CCKAR | Human | Cholecystokinin | A | pKi | 8.02 | 8.02 | 8.02 | Drug Central |
CCK2 | GASR | Human | Cholecystokinin | A | pKi | 8.02 | 8.02 | 8.02 | Drug Central |
CCK2 | GASR | Rat | Cholecystokinin | A | pKi | 8.03 | 8.03 | 8.03 | Drug Central |
CCK1 | CCKAR | Guinea pig | Cholecystokinin | A | pKi | 8.02 | 8.02 | 8.02 | Drug Central |
CCK1 | CCKAR | Rat | Cholecystokinin | A | pKi | 8.0 | 8.0 | 8.0 | Drug Central |
CCK2 | GASR | Human | Cholecystokinin | A | pKi | 9.19 | 9.43 | 9.55 | ChEMBL |
CCK1 | CCKAR | Guinea pig | Cholecystokinin | A | pKi | 9.15 | 9.27 | 9.55 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
CCK1 | CCKAR | Rat | Cholecystokinin | A | pIC50 | 8.55 | 8.55 | 8.55 | Guide to Pharmacology |
CCK2 | GASR | Rat | Cholecystokinin | A | pIC50 | 8.22 | 8.39 | 9.0 | ChEMBL |
CCK2 | GASR | Rat | Cholecystokinin | A | pEC50 | 9.2 | 9.2 | 9.2 | ChEMBL |
CCK1 | CCKAR | Rat | Cholecystokinin | A | pIC50 | 8.97 | 9.39 | 10.0 | ChEMBL |
CCK1 | CCKAR | Human | Cholecystokinin | A | pIC50 | 8.88 | 9.33 | 9.95 | ChEMBL |
CCK1 | CCKAR | Human | Cholecystokinin | A | pEC50 | 7.55 | 8.87 | 10.36 | ChEMBL |
CCK2 | GASR | Mouse | Cholecystokinin | A | pIC50 | 8.02 | 8.02 | 8.02 | Drug Central |
CCK2 | GASR | Human | Cholecystokinin | A | pEC50 | 7.57 | 8.95 | 10.3 | ChEMBL |
CCK2 | GASR | Human | Cholecystokinin | A | pIC50 | 8.09 | 9.38 | 9.92 | ChEMBL |
CCK2 | GASR | Human | Cholecystokinin | A | pIC50 | 9.9 | 9.95 | 10.0 | Guide to Pharmacology |
CCK2 | GASR | Mouse | Cholecystokinin | A | pIC50 | 8.89 | 9.41 | 9.52 | ChEMBL |
CCK1 | CCKAR | Guinea pig | Cholecystokinin | A | pIC50 | 9.4 | 9.48 | 9.55 | ChEMBL |