CHEMBL1935572


SMILES CN1CCN(c2nc(N)nc3cc(-c4ccsc4)ccc23)CC1
InChIKey PRWLDKKWXOINJS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 325.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Human Histamine A pKi 5.55 5.55 5.55 ChEMBL
H3 HRH3 Human Histamine A pKi 7.2 7.2 7.2 ChEMBL
H4 HRH4 Human Histamine A pKi 8.4 8.46 8.52 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pIC50 7.34 7.34 7.34 ChEMBL