CHEMBL1946254


SMILES Clc1ccc(N2CCCN(CCCCc3nc4ccccc4s3)CC2)cc1
InChIKey UNTNFKPMHAXOEK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 399.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 7.54 7.54 7.54 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.38 6.38 6.38 ChEMBL
H1 HRH1 Human Histamine A pKi 7.21 7.21 7.21 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.85 5.85 5.85 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.82 6.82 6.82 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.8 6.8 6.8 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.58 6.58 6.58 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.59 6.59 6.59 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database