Chembl211040

Chemical Properties

SMILES O=C(Nc1cc(-c2ccccc2)nn1-c1ccccc1)c1ccc(OC(F)(F)F)cc1
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight 423.1

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey VVZIZFWZHDLBGC-UHFFFAOYSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pKi 6.58 6.58 6.58 ChEMBL
mGlu5 GRM5 Rat Metabotropic glutamate C pEC50 7.75 7.75 7.75 ChEMBL