CHEMBL1951659


SMILES Cc1ccc(-n2ccc3c(sc4nccc(N(C)C)c43)c2=O)cc1
InChIKey FKCGAOJXLFANNO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 2
Molecular weight (Da) 335.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu1 GRM1 Rat Metabotropic glutamate C pKi 8.72 8.72 8.72 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu1 GRM1 Human Metabotropic glutamate C pIC50 8.33 8.33 8.33 ChEMBL
mGlu5 GRM5 Human Metabotropic glutamate C pIC50 5.92 5.92 5.92 ChEMBL