CHEMBL195247


SMILES O=S(=O)(NCCCCN1CCN(c2cccc(Cl)c2Cl)CC1)c1ccc(F)cc1
InChIKey FGJYYZXNIMNFLL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 459.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 5.75 5.75 5.75 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.77 7.77 7.77 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.8 7.8 7.8 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.92 6.92 6.92 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.31 7.36 7.41 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database