compound 22 [PMID: 19289283]


SMILES OCCOCCNc1ncc2c(c1)c(ncn2)NC1Cc2c(C1)cccc2
InChIKey QFBGUCZGHVJUGC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 8
Molecular weight (Da) 365.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu1 GRM1 Rat Metabotropic glutamate C pKi 8.52 8.52 8.52 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu1 GRM1 Rat Metabotropic glutamate C pIC50 8.52 8.52 8.52 Guide to Pharmacology
mGlu1 GRM1 Human Metabotropic glutamate C pIC50 8.52 8.52 8.52 ChEMBL